RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumors

Most transformed cells display abnormally high levels of RNA polymerase (pol) III transcripts. Although the full significance of this is unclear, it may be fundamental because healthy cells use two key tumor suppressors to restrain pol III activity. We present the first evidence that a pol III trans...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Winter, Andrew G., Sourvinos, George, Allison, Simon J., Tosh, Kerrie, Scott, Pamela H., Spandidos, Demetrios A., White, Robert J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.230224097
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