Accumulation of a newly developed fluoroquinolone, OPC-17116, by human polymorphonuclear leukocytes.

The accumulation of OPC-17116 by human polymorphonuclear leukocytes was studied by comparison with three other new quinolones, ofloxacin, levofloxacin, and DR-3354. The intracellular/extracellular concentration ratio was the highest for OPC-17116, being 66.2, followed by 9.8 for levofloxacin, 7.6 fo...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Taira, K, Koga, H, Kohno, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239600/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1877
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