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Accumulation of a newly developed fluoroquinolone, OPC-17116, by human polymorphonuclear leukocytes.

The accumulation of OPC-17116 by human polymorphonuclear leukocytes was studied by comparison with three other new quinolones, ofloxacin, levofloxacin, and DR-3354. The intracellular/extracellular concentration ratio was the highest for OPC-17116, being 66.2, followed by 9.8 for levofloxacin, 7.6 fo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Taira, K, Koga, H, Kohno, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188086/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239600/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1877
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