Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model.

Five topoisomerase II inhibitors (amsacrine [m-AMSA], two epipodophyllotoxins, and two quinolones) and the alkaloid camptothecin (a topoisomerase I inhibitor) were evaluated to assess their activities against Pneumocystis carinii. In vitro, both etoposide (VP-16) and teniposide (VM-26) at 1 microgra...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Fishman, J A, Queener, S F, Roth, R S, Bartlett, M S
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC188010/
https://ncbi.nlm.nih.gov/pubmed/8395791
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