Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model.

Five topoisomerase II inhibitors (amsacrine [m-AMSA], two epipodophyllotoxins, and two quinolones) and the alkaloid camptothecin (a topoisomerase I inhibitor) were evaluated to assess their activities against Pneumocystis carinii. In vitro, both etoposide (VP-16) and teniposide (VM-26) at 1 microgra...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Fishman, J A, Queener, S F, Roth, R S, Bartlett, M S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188010/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8395791/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.7.1543
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