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Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease.

We report the effects of ketoconazole and the bistriazole ICI 195,739 acting alone or in combination with the allylamine terbinafine (Lamisil) on murine models of Chagas' disease. Mice infected with 10(5) Trypanosoma (Schizotrypanum) cruzi blood trypomastigotes and treated orally with 30 mg of ketoc...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Maldonado, R A, Molina, J, Payares, G, Urbina, J A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187965/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8328786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1353
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