A rapid method for screening antimicrobial agents for activities against a strain of Mycobacterium tuberculosis expressing firefly luciferase.

We developed a rapid method to screen the efficacy of antimicrobial agents against Mycobacterium tuberculosis. A restriction fragment carrying a promoterless firefly luciferase gene was cloned into a 4,488-bp shuttle vector, pMV261, and luciferase was expressed under the control of a mycobacterial h...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Cooksey, R C, Crawford, J T, Jacobs, W R, Shinnick, T M
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187964/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8328785/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1348
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