Inhibition of Pneumocystis carinii dihydropteroate synthetase by para-acetamidobenzoic acid: possible mechanism of action of isoprinosine in human immunodeficiency virus infection.

Isoprinosine has been reported to decrease progression to AIDS, primarily by preventing Pneumocystis carinii pneumonia (PCP), in human immunodeficiency virus-infected patients, but the mechanism of action is unknown. para-Acetamidobenzoic acid (PAcBA), one component of isoprinosine, is structurally...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Kovacs, J A, Powell, F, Voeller, D, Allegra, C J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1227
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