Use of an in vivo system to determine the G418 resistance phenotype of bloodstream-form Trypanosoma brucei brucei transfectants.

We determined the level of susceptibility of Trypanosoma brucei brucei to the aminoglycoside G418 in vivo and demonstrated that it is possible to select for G418-resistant transfected T. brucei brucei bloodstream parasites in a mouse host by inoculating the drug intraperitoneally at doses between 40...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Murphy, N B, Muthiani, A M, Peregrine, A S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8517708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.1167
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