Use of an in vivo system to determine the G418 resistance phenotype of bloodstream-form Trypanosoma brucei brucei transfectants.

We determined the level of susceptibility of Trypanosoma brucei brucei to the aminoglycoside G418 in vivo and demonstrated that it is possible to select for G418-resistant transfected T. brucei brucei bloodstream parasites in a mouse host by inoculating the drug intraperitoneally at doses between 40...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Murphy, N B, Muthiani, A M, Peregrine, A S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8517708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.1167
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