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Defective double-strand DNA break repair and chromosomal translocations by MYC overexpression

DNA repair mechanisms are essential for the maintenance of genomic integrity. Disruption of gene products responsible for DNA repair can result in chromosomal damage. Improperly repaired chromosomal damage can result in the loss of chromosomes or the generation of chromosomal deletions or translocat...

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Autors principals: Karlsson, Asa, Deb-Basu, Debabrita, Cherry, Athena, Turner, Stephanie, Ford, James, Felsher, Dean W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC187906/
https://ncbi.nlm.nih.gov/pubmed/12909717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1732638100
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