Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II–deficient mice

Heparin cofactor II (HCII) specifically inhibits thrombin action at sites of injured arterial wall, and patients with HCII deficiency exhibit advanced atherosclerosis. However, the in vivo effects and the molecular mechanism underlying the action of HCII during vascular remodeling remain elusive. To...

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Xehetasun bibliografikoak
Egile Nagusiak: Aihara, Ken-ichi, Azuma, Hiroyuki, Akaike, Masashi, Ikeda, Yasumasa, Sata, Masataka, Takamori, Nobuyuki, Yagi, Shusuke, Iwase, Takashi, Sumitomo, Yuka, Kawano, Hirotaka, Yamada, Takashi, Fukuda, Toru, Matsumoto, Takahiro, Sekine, Keisuke, Sato, Takashi, Nakamichi, Yuko, Yamamoto, Yoko, Yoshimura, Kimihiro, Watanabe, Tomoyuki, Nakamura, Takashi, Oomizu, Akimasa, Tsukada, Minoru, Hayashi, Hideki, Sudo, Toshiki, Kato, Shigeaki, Matsumoto, Toshio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2007
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1878511/
https://ncbi.nlm.nih.gov/pubmed/17549254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27095
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