Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II–deficient mice

Heparin cofactor II (HCII) specifically inhibits thrombin action at sites of injured arterial wall, and patients with HCII deficiency exhibit advanced atherosclerosis. However, the in vivo effects and the molecular mechanism underlying the action of HCII during vascular remodeling remain elusive. To...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Aihara, Ken-ichi, Azuma, Hiroyuki, Akaike, Masashi, Ikeda, Yasumasa, Sata, Masataka, Takamori, Nobuyuki, Yagi, Shusuke, Iwase, Takashi, Sumitomo, Yuka, Kawano, Hirotaka, Yamada, Takashi, Fukuda, Toru, Matsumoto, Takahiro, Sekine, Keisuke, Sato, Takashi, Nakamichi, Yuko, Yamamoto, Yoko, Yoshimura, Kimihiro, Watanabe, Tomoyuki, Nakamura, Takashi, Oomizu, Akimasa, Tsukada, Minoru, Hayashi, Hideki, Sudo, Toshiki, Kato, Shigeaki, Matsumoto, Toshio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2007
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1878511/
https://ncbi.nlm.nih.gov/pubmed/17549254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27095
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