Androgen receptor promotes sex-independent angiogenesis in response to ischemia and is required for activation of vascular endothelial cell growth factor receptor signaling

BACKGROUND: Hypoandrogenemia is associated with an increased risk of ischemic diseases. Since actions of androgens are exerted through androgen receptor (AR) activation, we studied hind limb ischemia in AR knockout (KO) mice to elucidate the role of AR in response to ischemia. METHODS AND RESULTS: B...

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Detalhes bibliográficos
Main Authors: Yoshida, Sumiko, Aihara, Ken-ichi, Ikeda, Yasumasa, Sumitomo-Ueda, Yuka, Uemoto, Ryoko, Ishikawa, Kazue, Ise, Takayuki, Yagi, Shusuke, Iwase, Takashi, Mouri, Yasuhiro, Sakari, Matomo, Matsumoto, Takahiro, Takeyama, Ken-ichi, Akaike, Masashi, Matsumoto, Mitsuru, Sata, Masataka, Walsh, Kenneth, Kato, Shigeaki, Matsumoto, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933182/
https://ncbi.nlm.nih.gov/pubmed/23723256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.001533
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