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Intrinsic Fluctuations, Robustness, and Tunability in Signaling Cycles
Covalent modification cycles (e.g., phosphorylation-dephosphorylation) underlie most cellular signaling and control processes. Low molecular copy number, arising from compartmental segregation and slow diffusion between compartments, potentially renders these cycles vulnerable to intrinsic chemical...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877790/ https://ncbi.nlm.nih.gov/pubmed/17400695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088856 |
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