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Operating Regimes of Signaling Cycles: Statics, Dynamics, and Noise Filtering

A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering that can be accomplished by this simple biochemical circuit. Signaling cycles are...

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Detalhes bibliográficos
Main Authors: Gomez-Uribe, Carlos, Verghese, George C, Mirny, Leonid A
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230677/
https://ncbi.nlm.nih.gov/pubmed/18159939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030246
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