Mechanism of action of quinolones against Escherichia coli DNA gyrase.

The mechanism of action of quinolones was investigated by use of various DNA gyrases reconstituted from wild-type and mutant GyrA and GyrB proteins of Escherichia coli. The quinolone sensitivities of the DNA supercoiling activity of the gyrases were generally parallel to the quinolone susceptibiliti...

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Main Authors: Yoshida, H, Nakamura, M, Bogaki, M, Ito, H, Kojima, T, Hattori, H, Nakamura, S
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC187778/
https://ncbi.nlm.nih.gov/pubmed/8388200
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