Mechanism of action of quinolones against Escherichia coli DNA gyrase.

The mechanism of action of quinolones was investigated by use of various DNA gyrases reconstituted from wild-type and mutant GyrA and GyrB proteins of Escherichia coli. The quinolone sensitivities of the DNA supercoiling activity of the gyrases were generally parallel to the quinolone susceptibiliti...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Yoshida, H, Nakamura, M, Bogaki, M, Ito, H, Kojima, T, Hattori, H, Nakamura, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8388200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.4.839
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