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Diffuse plaques do not accentuate synapse loss in Alzheimer's disease.
Applying the relatively new technique of laser confocal imaging, vibratome sections which were double immunolabeled for amyloid beta protein and the presynaptic terminal marker synaptophysin were examined. It was found that while synaptic density was generally diminished in Alzheimer's disease...
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Autores principales: | , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
1990
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877714/ https://ncbi.nlm.nih.gov/pubmed/2124413 |
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