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Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease.

We have recently identified, in the brain tissue of patients afflicted with Alzheimer's disease (AD), the non-A beta component of AD amyloid (NAC) as a new constituent of amyloid. NAC is derived from a larger precursor, NACP, a presynaptic protein. To better understand the role of NACP/NAC in t...

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Detalles Bibliográficos
Autores principales: Masliah, E., Iwai, A., Mallory, M., Uéda, K., Saitoh, T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1861620/
https://ncbi.nlm.nih.gov/pubmed/8546207
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