Caspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's disease
The principal pathological features of Alzheimer's disease (AD) are extracellular amyloid plaques and intracellular neurofibrillary tangles, the latter composed of the microtubule-binding protein tau assembled into paired helical and straight filaments. Recent studies suggest that these pathological...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1630428100 |
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