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Glomerular lesions in mice transgenic for growth hormone and insulinlike growth factor-I. I. Relationship between increased glomerular size and mesangial sclerosis.

The glomeruli of mice transgenic for bovine growth hormone (GH mice) were disproportionately enlarged as a function of either kidney or body weight. Glomerular size correlated with mesangial sclerosis and the urine albumin/creatinine ratio. The glomerular lesions consisted of mesangial proliferation...

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Bibliografiske detaljer
Main Authors: Doi, T., Striker, L. J., Gibson, C. C., Agodoa, L. Y., Brinster, R. L., Striker, G. E.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877515/
https://ncbi.nlm.nih.gov/pubmed/2399934
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