The role of Rel(Mtb)-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice

Long-term survival of nonreplicating Mycobacterium tuberculosis (Mtb) is ensured by the coordinated shutdown of active metabolism through a broad transcriptional program called the stringent response. In Mtb, this response is initiated by the enzymatic action of Rel(Mtb) and deletion of rel(Mtb) pro...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Dahl, John L., Kraus, Carl N., Boshoff, Helena I. M., Doan, Bernard, Foley, Korrie, Avarbock, David, Kaplan, Gilla, Mizrahi, Valerie, Rubin, Harvey, Barry, Clifton E.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1631248100
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