Pharmacokinetics and bactericidal activities of one 800-milligram dose versus two 400-milligram doses of intravenously administered pefloxacin in healthy volunteers.

Pefloxacin pharmacokinetics and serum bactericidal activities (SBA) against Escherichia coli and Staphylococcus aureus were compared after intravenous infusion of either a single 800-mg dose or twice-daily 400-mg doses into 16 healthy volunteers. Plasma pefloxacin concentrations were measured for up...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Petitjean, O, Pangon, B, Brion, N, Tod, M, Chaplain, C, Le Gros, V, Louchahi, K, Allouch, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187746/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8494368/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.4.737
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