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2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81) potently inhibits human cytomegalovirus replication and potentiates the antiviral effects of ganciclovir.

We studied the effects of 2-acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81 or A1110U), a potent inhibitor of the ribonucleotide reductases encoded by herpes simplex virus types 1 and 2 and by varicella-zoster virus, against human cytomegalovirus (HCMV) replication in in...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Hamzeh, F M, Spector, T, Lietman, P S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187714/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384821/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.3.602
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