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Nucleotide Exchange Factors for Hsp70s Are Required for [URE3] Prion Propagation in Saccharomyces cerevisiae

The [URE3] and [PSI(+)] prions are infectious amyloid forms of Ure2p and Sup35p. Several chaperones influence prion propagation: Hsp104p overproduction destabilizes [PSI(+)], whereas [URE3] is sensitive to excess of Ssa1p or Ydj1p. Here, we show that overproduction of the chaperone, Sse1p, can effic...

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Bibliografiske detaljer
Main Authors: Kryndushkin, Dmitry, Wickner, Reed B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877104/
https://ncbi.nlm.nih.gov/pubmed/17392510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0128
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