Statins (HMG-CoA Reductase Inhibitors) Decrease Postoperative Adhesions by Increasing Peritoneal Fibrinolytic Activity

OBJECTIVES: The aims of this study were to determine if statins reduce adhesion formation in vivo and to identify the mechanism of action in vitro. BACKGROUND: Intraperitoneal adhesions develop in up to 95% of patients following laparotomy. Adhesions are reduced by mechanisms that up-regulate fibrin...

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Main Authors: Aarons, Cary B., Cohen, Philip A., Gower, Adam, Reed, Karen L., Leeman, Susan E., Stucchi, Arthur F., Becker, James M.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876993/
https://ncbi.nlm.nih.gov/pubmed/17245169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000236627.07927.7c
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