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HIPPOCAMPAL SEIZURES CAUSE DEPOLYMERIZATION OF FILAMENTOUS ACTIN IN NEURONS INDEPENDENT OF ACUTE MORPHOLOGICAL CHANGES

Seizures may exert pathophysiological effects on dendritic spines, but the molecular mechanisms mediating these effects are poorly understood. Actin represents a major structural protein of dendritic spines, and actin filaments (F-actin) can be depolymerized by the regulatory molecule, cofilin, lead...

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Main Authors: Ouyang, Yannan, Yang, Xiao-Feng, Hu, Xiao Yan, Erbayat-Altay, Ebru, Zeng, Ling-Hui, Lee, Jin-Moo, Wong, Michael
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876944/
https://ncbi.nlm.nih.gov/pubmed/17320053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.01.077
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