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HIPPOCAMPAL SEIZURES CAUSE DEPOLYMERIZATION OF FILAMENTOUS ACTIN IN NEURONS INDEPENDENT OF ACUTE MORPHOLOGICAL CHANGES

Seizures may exert pathophysiological effects on dendritic spines, but the molecular mechanisms mediating these effects are poorly understood. Actin represents a major structural protein of dendritic spines, and actin filaments (F-actin) can be depolymerized by the regulatory molecule, cofilin, lead...

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Autori principali: Ouyang, Yannan, Yang, Xiao-Feng, Hu, Xiao Yan, Erbayat-Altay, Ebru, Zeng, Ling-Hui, Lee, Jin-Moo, Wong, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876944/
https://ncbi.nlm.nih.gov/pubmed/17320053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2007.01.077
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