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Cytokeratin 8 Protects from Hepatotoxicity, and Its Ratio to Cytokeratin 18 Determines the Ability of Hepatocytes to Form Mallory Bodies

In alcoholic hepatitis, a severe form of alcohol-induced toxic liver injury, as well as in experimental intoxication of mice with the porphyrinogenic drugs griseofulvin and 3,5-diethoxycarbonyl-1,4-dihydrocollidine, hepatocytes form cytoplasmic protein aggregates (Mallory bodies; MBs) containing cyt...

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Detalhes bibliográficos
Main Authors: Zatloukal, Kurt, Stumptner, Cornelia, Lehner, Manfred, Denk, Helmut, Baribault, Helene, Eshkind, Leonid G., Franke, Werner W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876873/
https://ncbi.nlm.nih.gov/pubmed/10751352
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