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Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26

A subset of prolyl oligopeptidases, including dipeptidyl-peptidase IV (DPP IV or CD26, EC 3.4.14.5), specifically cleave off N-terminal dipeptides from substrates having proline or alanine in amino acid position 2. This enzyme activity has been implicated in the regulation of the biological activity...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Marguet, Didier, Baggio, Laurie, Kobayashi, Takashi, Bernard, Anne-Marie, Pierres, Michel, Nielsen, Per F., Ribel, Ulla, Watanabe, Takeshi, Drucker, Daniel J., Wagtmann, Nicolai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10823914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.120069197
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