Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26

A subset of prolyl oligopeptidases, including dipeptidyl-peptidase IV (DPP IV or CD26, EC 3.4.14.5), specifically cleave off N-terminal dipeptides from substrates having proline or alanine in amino acid position 2. This enzyme activity has been implicated in the regulation of the biological activity...

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Main Authors: Marguet, Didier, Baggio, Laurie, Kobayashi, Takashi, Bernard, Anne-Marie, Pierres, Michel, Nielsen, Per F., Ribel, Ulla, Watanabe, Takeshi, Drucker, Daniel J., Wagtmann, Nicolai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18768/
https://ncbi.nlm.nih.gov/pubmed/10823914
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