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Activating c-kit Gene Mutations in Human Germ Cell Tumors

The c-kit gene encodes a tyrosine kinase receptor (KIT) that is required in normal spermatogenesis and is expressed in seminomas and dysgerminomas, a subset of human germ cell tumors (GCTs). To determine whether activating mutations of the c-kit gene occur in GCTs, primary tissue samples of 33 testi...

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Auteurs principaux: Tian, Qingsheng, Frierson, Henry F., Krystal, Geoffrey W., Moskaluk, Christopher A.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876773/
https://ncbi.nlm.nih.gov/pubmed/10362788
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