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Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.

p193/CUL7 is an E3 ubiquitin ligase initially identified as an SV40 Large T Antigen binding protein. Expression of a dominant interfering variant of mouse p193/CUL7 (designated 1152stop) conferred resistance to MG132- and etoposide-induced apoptosis in U2OS cells. Immune precipitation/Western analys...

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Bibliografski detalji
Glavni autori: Dowell, Joshua D., Tsai, Shih-Chong, Dias-Santagata, Dora C., Nakajima, Hidehiro, Wang, Zhuo, Zhu, Wuqiang, Field, Loren J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876763/
https://ncbi.nlm.nih.gov/pubmed/17229476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2006.11.020
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