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Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2
The active site topology, substrate specificity, and biological roles of the human cytochrome P450 CYP2J2, which is mainly expressed in the cardiovascular system, are poorly known even though recent data suggest that it could be a novel biomarker and potential target for therapy of human cancer. Thi...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876728/ https://ncbi.nlm.nih.gov/pubmed/16495056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.02.004 |
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