Загрузка...

Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2

The active site topology, substrate specificity, and biological roles of the human cytochrome P450 CYP2J2, which is mainly expressed in the cardiovascular system, are poorly known even though recent data suggest that it could be a novel biomarker and potential target for therapy of human cancer. Thi...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Lafite, Pierre, Dijols, Sylvie, Buisson, Didier, Macherey, Anne-Christine, Zeldin, Darryl C., Dansette, Patrick M., Mansuy, Daniel
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876728/
https://ncbi.nlm.nih.gov/pubmed/16495056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.02.004
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!