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Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function

The basic helix–loop–helix transcriptional repressor Hairy-related transcription factor 2 (Hrt2) is expressed in ventricular, but not atrial, cardiomyocytes, and in endothelial and vascular smooth muscle cells. Mice homozygous for a null mutation of Hrt2 die perinatally from a spectrum of cardiac ab...

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Bibliografische gegevens
Hoofdauteurs: Xin, Mei, Small, Eric M., van Rooij, Eva, Qi, Xiaoxia, Richardson, James A., Srivastava, Deepak, Nakagawa, Osamu, Olson, Eric N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876557/
https://ncbi.nlm.nih.gov/pubmed/17468400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702447104
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