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Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel

It is now well established that the voltage-sensing S4 segment in voltage-dependent ion channels undergoes a conformational change in response to varying membrane potential. However, the magnitude of the movement of S4 relative to the membrane and the rest of the protein remains controversial. Here,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Campos, Fabiana V., Chanda, Baron, Roux, Benoît, Bezanilla, Francisco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876545/
https://ncbi.nlm.nih.gov/pubmed/17470814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702638104
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