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Probing a moving target with a plastic unfolding intermediate of an ankyrin-repeat protein

Repeat proteins are composed of tandem arrays of 30- to 40-residue structural motifs and are characterized by short-range interactions between residues close in sequence. Here we have investigated the equilibrium unfolding of D34, a 426-residue fragment of ankyrinR that comprises 12 ankyrin repeats....

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Detalhes bibliográficos
Main Authors: Werbeck, Nicolas D., Itzhaki, Laura S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876538/
https://ncbi.nlm.nih.gov/pubmed/17483458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610315104
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