Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers.

Some macrolide antibiotics cause clinical drug interactions, resulting in altered metabolism of concomitantly administered drugs, via formation of an inactive cytochrome P-450 complex. In the present study, the formation of a cytochrome P-450 type I binding spectrum and a metabolic intermediate comp...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Lindstrom, T D, Hanssen, B R, Wrighton, S A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8452357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.2.265
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