Low neurotoxicity of LJC 10,627, a novel 1 beta-methyl carbapenem antibiotic: inhibition of gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in relation to lack of central nervous system toxicity in rats.
The toxicity of LJC 10,627 to the central nervous system of rats was evaluated by examining the effects of the compound on gamma-aminobutyric acidA, benzodiazepine, and glycine receptor binding in rat synaptic membranes and on the induction of behavioral convulsions by intraventricular administratio...
Na minha lista:
| Udgivet i: | Antimicrob Agents Chemother |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187638/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383938/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.2.199 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|