In vitro evaluation of phosphorothioate oligonucleotides targeted to the E2 mRNA of papillomavirus: potential treatment for genital warts.

Papillomaviruses induce benign proliferative lesions, such as genital warts, in humans. The E2 gene product is thought to play a major role in the regulation of viral transcription and DNA replication and may represent a rational target for an antisense oligonucleotide drug action. Phosphorothioate...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Cowsert, L M, Fox, M C, Zon, G, Mirabelli, C K
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187633/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383937/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.2.171
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