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A full Bayesian hierarchical mixture model for the variance of gene differential expression

BACKGROUND: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccurate. Visual inspection of graphical summaries of these data usually reveals that heteroscedasticity is present, and the s...

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Détails bibliographiques
Auteurs principaux: Manda, Samuel OM, Walls, Rebecca E, Gilthorpe, Mark S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876253/
https://ncbi.nlm.nih.gov/pubmed/17439644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-124
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