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A full Bayesian hierarchical mixture model for the variance of gene differential expression

BACKGROUND: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccurate. Visual inspection of graphical summaries of these data usually reveals that heteroscedasticity is present, and the s...

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Bibliografiske detaljer
Main Authors: Manda, Samuel OM, Walls, Rebecca E, Gilthorpe, Mark S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876253/
https://ncbi.nlm.nih.gov/pubmed/17439644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-124
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