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A full Bayesian hierarchical mixture model for the variance of gene differential expression

BACKGROUND: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccurate. Visual inspection of graphical summaries of these data usually reveals that heteroscedasticity is present, and the s...

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Detalhes bibliográficos
Main Authors: Manda, Samuel OM, Walls, Rebecca E, Gilthorpe, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876253/
https://ncbi.nlm.nih.gov/pubmed/17439644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-124
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