Hyperoxia and prolongation of aminoglycoside-induced postantibiotic effect in Pseudomonas aeruginosa: role of reactive oxygen species.

Hyperoxia prolongs the postantibiotic effect (PAE) of the aminoglycoside tobramycin in Pseudomonas aeruginosa. We tested the hypothesis that the PAE is prolonged because hyperoxia increases free radical flux while tobramycin inhibits the induction of antioxidant defenses. Exposure of P. aeruginosa t...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Park, M K, Myers, R A, Marzella, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8431008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.1.120
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