Hyperoxia and prolongation of aminoglycoside-induced postantibiotic effect in Pseudomonas aeruginosa: role of reactive oxygen species.

Hyperoxia prolongs the postantibiotic effect (PAE) of the aminoglycoside tobramycin in Pseudomonas aeruginosa. We tested the hypothesis that the PAE is prolonged because hyperoxia increases free radical flux while tobramycin inhibits the induction of antioxidant defenses. Exposure of P. aeruginosa t...

Full description

Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Park, M K, Myers, R A, Marzella, L
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1993
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8431008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.1.120
Tags:	Add Tag No Tags, Be the first to tag this record!