A Novel Method for SNP Detection Using a New Duplex-Specific Nuclease From Crab Hepatopancreas

We have characterized a novel nuclease from the Kamchatka crab, designated duplex-specific nuclease (DSN). DSN displays a strong preference for cleaving double-stranded DNA and DNA in DNA-RNA hybrid duplexes, compared to single-stranded DNA. Moreover, the cleavage rate of short, perfectly matched DN...

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Autors principals: Shagin, Dmitry A., Rebrikov, Denis V., Kozhemyako, Valery B., Altshuler, Ilia M., Shcheglov, Alex S., Zhulidov, Pavel A., Bogdanova, Ekaterina A., Staroverov, Dmitry B., Rasskazov, Valery A., Lukyanov, Sergey
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
Matèries:
Methods
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC187582/
https://ncbi.nlm.nih.gov/pubmed/12466298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.547002
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