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In Silico Model-Driven Assessment of the Effects of Single Nucleotide Polymorphisms (SNPs) on Human Red Blood Cell Metabolism

The completion of the human genome project and the construction of single nucleotide polymorphism (SNP) maps have lead to significant efforts to find SNPs that can be linked to pathophysiology. In silico models of complete biochemical reaction networks relate a cell's individual reactions to th...

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Autores principales: Jamshidi, Neema, Wiback, Sharon J., Palsson, Bernhard Ø.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC187553/
https://ncbi.nlm.nih.gov/pubmed/12421755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.329302
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