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Signatures of Domain Shuffling in the Human Genome

To elucidate the role of exon shuffling in shaping the complexity of the human genome/proteome, we have systematically analyzed intron phase distributions in the coding sequence of human protein domains. We found that introns at the boundaries of domains show high excess of symmetrical phase combina...

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Autori principali: Kaessmann, Henrik, Zöllner, Sebastian, Nekrutenko, Anton, Li, Wen-Hsiung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC187552/
https://ncbi.nlm.nih.gov/pubmed/12421750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.520702
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