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The K(A)/K(S) Ratio Test for Assessing the Protein-Coding Potential of Genomic Regions: An Empirical and Simulation Study

Comparative genomics is a simple, powerful way to increase the accuracy of gene prediction. In this study, we show the utility of a simple test for the identification of protein-coding exons using human/mouse sequence comparisons. The test takes advantage of the fact that in the vast majority of cod...

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Autors principals: Nekrutenko, Anton, Makova, Kateryna D., Li, Wen-Hsiung
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155263/
https://ncbi.nlm.nih.gov/pubmed/11779845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.200901
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