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Judging the Quality of Gene Expression-Based Clustering Methods Using Gene Annotation

We compare several commonly used expression-based gene clustering algorithms using a figure of merit based on the mutual information between cluster membership and known gene attributes. By studying various publicly available expression data sets we conclude that enrichment of clusters for biologica...

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Detalhes bibliográficos
Main Authors: Gibbons, Francis D., Roth, Frederick P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187526/
https://ncbi.nlm.nih.gov/pubmed/12368250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.397002
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